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- Diabetes may weaken teeth and promote tooth decay
Inducing Type 1 diabetes in mice significantly reduced enamel and dentin microhardness.
- U.S. study analyzing tooth survival after root canal in general population
Oral health is a public health issue that significantly affects people's overall health. A ground-breaking study of root canal longevity using electronic dental record data from 46,000 root canal patients treated in community dental practices found geographic and procedure disparities, providing real-world insight that can be used to inform dental practice.
- How one inflammatory disorder exacerbates another
People with severe gum disease are at a higher risk of other inflammatory conditions, such as heart disease and arthritis, and the reverse is true as well. New research unpacks the mechanism underlying this association, demonstrating in mice that a susceptibility to arthritis can be transmitted by a bone marrow transplant if the donor has gum inflammation.
- Could blocking or deleting a protein help prevent common oral cancers?
Around one-third of people with oral squamous cell carcinoma don't survive it, but dental researchers have found deleting or inhibiting a protein in the tongue might stall tumor growth.
- Wearing dentures may affect a person's nutrition
Dentures may have a potentially negative impact on a person's overall nutrition, according to new research. The research team leveraged electronic dental and health records of 10,000+ patients to gain a better understanding of how oral health treatments affect individuals' overall health over time. The study found that people with dentures had a significant decline in nutrition markers. People who did not wear dentures did not experience this decline. This is believed to be the first study to report results of utilizing lab values of nutritional biomarkers and linking them with dental records.
- Researchers take important step towards development of biological dental enamel
To this day, cavities and damage to enamel are repaired by dentists with the help of synthetic white filling materials. There is no natural alternative to this. But a new 3D model with human dental stem cells could change this in the future.
- Study helps explain how xanthan gum, a common food additive, is processed in the gut
A new study examines the ability of the human gut microbiome to digest xanthan gum, a relatively recently introduced food ingredient found in many processed foods.
- Newly identified cell type could be the key to restoring damaged salivary glands
Scientists have discovered a special type of cell that resides in salivary glands and is likely crucial for oral health.
- Carbs, sugary foods may influence poor oral health
New research on postmenopausal women identifies associations between commonly eaten foods and the diversity and composition of oral bacteria.
- New dental tool prototype can spot the acidic conditions that lead to cavities
Researchers have shown that a dental tool they created can measure the acidity built up by the bacteria in plaque that leads to cavities.
- Nocturnal teeth grinding can damage temporomandibular joints
Nocturnal teeth grinding and clenching of the upper and lower jaw are known as sleep bruxism and can have a number of consequences for health. In dental science, the question of whether sleep bruxism is associated with the development or progression of temporomandibular joint disorders is controversial. New research shows that certain tooth shapes and tooth locations could well lead to temporomandibular joint problems as a result of bruxism.
- Some oral bacteria linked with hypertension in older women
In a study of more than 1,200 women in the U.S., average age 63 years, 10 kinds of oral bacteria were associated with a higher risk of developing high blood pressure, while five strains of bacteria were linked with lower hypertension risk. The observational study cannot prove cause and effect; however, the findings highlight possible opportunities to enhance hypertension prevention through targeted oral care, researchers said.
- Evidence grows for vaping's role in gum disease
New studies highlight how e-cigarettes alter oral health and may be contributing to gum disease. The latest research finds that e-cigarette users have a unique oral microbiome that is less healthy than nonsmokers but potentially healthier than cigarette smokers, and measures worsening gum disease over time.
- Less antibiotic use in dentistry gave no increase in endocarditis
Sweden is one of the few countries that have removed the dental health recommendation to give prophylactic antibiotics to people at a higher risk of infection of the heart valves, so-called infective endocarditis. Since the recommendation was removed in 2012, there has been no increase in this disease, a registry study shows.
- Living in a microbial world: The healthy oral microbiome contributes to jaw bone health by influencing immune cell interactions with bone cells
Researchers have shown that commensal microbes in the mouth, in contrast to commensal microbes colonizing other body surfaces, e.g., the gut or skin, modulate immune responses in the jaw bone that promote bone-resorbing osteoclasts and bone loss. In a preclinical model, depleting healthy commensal microbes in the mouth, using an antiseptic oral rinse, was shown to protect against this bone loss.
- Social isolation among older adults linked to having fewer teeth
Older adults who are socially isolated are more likely to have missing teeth--and to lose their teeth more quickly over time--than those with more social interaction, according to a new study of Chinese older adults.
- How oral bacteria suppress protection against viral growth
Researchers have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of these cells, increasing vulnerability to infection.
- Researchers gain insights into how ultrasmall bacteria from the environment have adapted to live inside humans
Scientists created a model system to experimentally study tiny bacteria called TM7 and provide empirical data to confirm a hypothesis for how the bacteria adapted to live inside humans.
- Disarming a blood-clotting protein prevents gum disease in mice
Blocking function of a blood-clotting protein, called fibrin, prevented bone loss from periodontal (gum) disease in mice, according to new research. The study suggests that suppressing abnormal fibrin activity could hold promise for preventing or treating periodontal disease, as well as other inflammatory disorders marked by fibrin buildup, including arthritis and multiple sclerosis.
- Gum disease increases risk of other illness such as mental health and heart conditions, study suggests
A new study shows an increased risk of patients developing illnesses including mental ill-health and heart conditions if they have a GP-inputted medical history of gum disease.
- A chewing gum that could reduce SARS-CoV-2 transmission
In experiments using saliva samples from COVID-19 patients, the gum, which contains the ACE2 protein, neutralized the virus, according to scientists.
- Obesity raises the risk of gum disease by inflating growth of bone-destroying cells
Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new research that sought to improve understanding of the connection between obesity and gum disease. The study, completed in an animal model and published in October in the Journal of Dental Research, found that excessive inflammation resulting from obesity raises the number of myeloid-derived suppressor cells (MDSC), a group of immune cells that increase during illness to regulate immune function. MDSCs, which originate in the bone marrow, develop into a range of different cell types, including osteoclasts (a cell that breaks down bone tissue).
- Baby teeth may one day help identify kids at risk for mental disorders later in life
The thickness of growth marks in primary (or 'baby') teeth may help identify children at risk for depression and other mental health disorders later in life, according to a ground-breaking investigation.
- ‘Nanozyme’ therapy prevents harmful dental plaque build-up
FDA-approved iron oxide nanoparticles, delivered in a mouth rinse, can suppress the growth of dental plaque and kill bacteria responsible for tooth decay, according to a new study. The nanoparticles act as enzymes to activate hydrogen peroxide in a way that precisely targets harmful microbes and spares normal tissue.
- New technique helps researchers understand how acid damages teeth
Researchers have developed a new technique to improve understanding of how acid damages teeth at the microstructural level.
- Heartburn drugs may have unexpected benefits on gum disease
New research found that patients who used drugs prescribed to treat heartburn, acid reflux and ulcers were more likely to have smaller probing depths in the gums (the gap between teeth and gums).
- A study of skull growth and tooth emergence reveals that timing is everything
Paleoanthropologists have wondered how and why humans evolved molars that emerge into the mouth at specific ages and why those ages are so delayed compared to living apes. It is the coordination between facial growth and the mechanics of the chewing muscles that determines not just where but when adult molars emerge. This results in molars coming in only when enough of a 'mechanically safe' space is created. Molars that emerge 'ahead of schedule' would do so in a space that, when chewed on, would disrupt the fine-tuned function of the entire chewing apparatus by causing damage to the jaw joint.
- Dental care: The best, worst and unproven tools to care for your teeth
Only a handful of oral hygiene tools actually prevent gum disease. At the moment, all other tools are only supported by insufficient evidence, say researchers.
- Smart dental implants
Researchers are developing a smart dental implant that resists bacterial growth and generates its own electricity through chewing and brushing to power a tissue-rejuvenating light. The innovation could extend the usable life of an implant.
- Whiter teeth, without the burn
Researchers report that they have developed a gel that, when exposed to near infrared (NIR) light, safely whitens teeth without the burn.
- Dental implant surfaces play major role in tissue attachment, warding off unwanted bacteria
The surface of implants, as well as other medical devices, plays a significant role in the adsorption of oral proteins and the colonization by unwanted microorganisms (a process known as biofouling), according to a new study.
- Setting the teeth on edge: Identifying the risk factors for tooth loss
Periodontitis, a form of severe gum infection, can lead to tooth loss and is linked with other diseases. Management of periodontitis remains difficult, partly due to inadequate understanding of risk factors associated with the condition. In a recent study from Japan, researchers have emphasized the role of oral microbiome, over an individual's genetic makeup, in the development of the disease, providing clinicians a guide to designing strategies for diagnosing and treating periodontitis.
- Research finds ‘very low rates’ of dental fluoride varnish treatment for young children
Fewer than 5% of well-child visits for privately insured young children included a recommended dental fluoride varnish application, despite mandatory insurance coverage for this service, according to a new study.
- Half of pediatric opioid prescriptions are 'high risk'
A new study suggests that children and young adults are frequently exposed to unsafe opioid prescriptions.
- Light therapy helps burn injuries heal faster by triggering growth protein
The research found that photobiomodulation -- a form of low-dose light therapy -- sped up recovery from burns and reduced inflammation in mice by activating a protein that controls cell growth and division.
- Good toothbrushing habits in children linked to mother's wellbeing
Researchers have shown that postpartum depression can inhibit a mother's ability to instill healthy tooth brushing habits in children. The study demonstrates the need to foster greater mental support and management for mothers and incorporate these factors when assessing children's oral health.
- Study reveals new aspects of gingivitis and body's response
Researchers have identified and classified how different people respond to the accumulation of dental plaque.
- Tooth loss associated with increased cognitive impairment, dementia
Tooth loss is a risk factor for cognitive impairment and dementia -- and with each tooth lost, the risk of cognitive decline grows, according to a new analysis.
- Mucus and mucins may become the medicine of the future
The body is filled with mucus that keeps track of the bacteria. Now, researchers present a method for producing artificial mucus. They hope that the artificial mucus, which consists of sugary molecules, may help to develop completely new, medical treatments.
- New report aims to improve VR use in healthcare education
A new report could help improve how immersive technologies such as Virtual Reality (VR) and Augmented Reality (AR) are used in healthcare education and training.
- Pulling wisdom teeth can improve long-term taste function, research finds
Patients who had their wisdom teeth extracted had improved tasting abilities decades after having the surgery, according to a new study.
- Predicting tooth loss
New research suggests that machine learning tools can help identify those at greatest risk for tooth loss and refer them for further dental assessment in an effort to ensure early interventions to avert or delay the condition.
- Gaps to fill: Income, education may impact inequalities in seeking dental care
A study examined a massive national claims dataset in search of regional and socioeconomic inequalities in the use of dental care services in Japan. This examination of millions of pieces of data found periodontal care and outreach services showed the widest regional inequalities. People in areas with lower education and income were more likely to seek treatment after dental diseases progress. More clinics and higher education and incomes correlated with earlier treatment.
- A link between childhood stress and early molars
Research shows that children from lower-income backgrounds and those who go through greater adverse childhood experiences get their first permanent molars sooner. The findings align with a broader pattern of accelerated development often seen under conditions of early-life stress.
- Rare mineral from rocks found in mollusk teeth
Researchers discovered a rare mineral hidden inside the teeth of a chiton, a large mollusk found along rocky coastlines. Before this strange surprise, the iron mineral, called santabarbaraite, only had been documented in rocks.
- A gentler strategy for avoiding childhood dental decay
By targeting the bonds between bacteria and yeast that can form a sticky dental plaque, a new therapeutic strategy could help wash away the build-up while sparing oral tissues, according to a new study.
- Dental procedures during pandemic are no riskier than a drink of water, study finds
A new study's findings dispel the misconception that patients and providers are at high risk of catching COVID-19 at the dentist's office.
- AI helps predict treatment outcomes for patients with diseased dental implants
Peri-implantitis, a condition where tissue and bone around dental implants becomes infected, besets roughly one-quarter of dental implant patients, and currently there's no reliable way to assess how patients will respond to treatment of this condition.
- Independent evolutionary origins of vertebrate dentitions
The origins of a pretty smile have long been sought in the fearsome jaws of living sharks which have been considered living fossils reflecting the ancestral condition for vertebrate tooth development and inference of its evolution. However, this view ignores real fossils which more accurately reflect the nature of ancient ancestors.
- Comprehensive single-cell atlas of human teeth
Researchers have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.
- Study shows 2 percent of asymptomatic pediatric dental patients test positive for COVID-19
A new study has shown a novel way to track potential COVID-19 cases -- testing children who visit the dentist. The study also showed an over 2 percent positivity rate for the asymptomatic children tested.
- Good dental health may help prevent heart infection from mouth bacteria
Good oral hygiene and regular dental care are the most important ways to reduce risk of a heart infection called infective endocarditis caused by bacteria in the mouth. There are four categories of heart patients considered to be at highest risk for adverse outcomes from infective endocarditis, and only these patients are recommended to receive preventive antibiotic treatment prior to invasive dental procedures.
- Imbalance in gum bacteria linked to Alzheimer's disease biomarker
Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta -- a key biomarker for Alzheimer's disease -- in their cerebrospinal fluid, according to new research. However, this imbalance in oral bacteria was not associated with another Alzheimer's biomarker called tau.
- New drug to regenerate lost teeth
Scientists report that an antibody for one gene -- uterine sensitization associated gene-1 or USAG-1 -- can stimulate tooth growth in mice suffering from tooth agenesis.
- People with severe gum disease may be twice as likely to have increased blood pressure
Research shows that periodontitis, severe gum disease, is linked to higher blood pressure in otherwise healthy individuals. This study of 500 adults with and without gum disease found that approximately 50% of adults could have undetected hypertension. Promotion of good oral health could help reduce gum disease and the risk of high blood pressure and its complications.
- How teeth sense the cold
An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches.
- Scientists find evidence that novel coronavirus infects the mouth's cells
Scientists has found evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. The findings point to the possibility that the mouth plays a role in transmitting SARS-CoV-2 to the lungs or digestive system via saliva laden with virus from infected oral cells. A better understanding of the mouth's involvement could inform strategies to reduce viral transmission within and outside the body.
- Dentists' tool boost as engineers get to root of tiny bubbles
People's teeth-chattering experiences in the dentist's chair could be improved by fresh insights into how tiny, powerful bubbles are formed by ultra-fast vibrations, a study suggests.
- Periodontal disease increases risk of major cardiovascular events
People with periodontitis are at higher risk of experiencing major cardiovascular events, according to new research.
- New hope for treating chronic pain without opioids
According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients -- a frustration that's often compounded by a hesitation to prescribe opioids for pain.
- Temporomandibular Joint Disorder
Temporomandibular joint disorder (TMD) describes a variety of conditions that affect jaw muscles, temporomandibular joints and nerves associated with chronic facial pain. Symptoms may occur on one or both sides of the face, head or jaw, or develop after an injury. TMD affects more than twice as many women than men. Updated: November 2008
- What is Dental Amalgam (Silver Filling)?
What is Dental Amalgam (Silver Fillings)? Most people recognize dental amalgams as silver fillings. Dental amalgam is a mixture of mercury, silver, tin and copper. Mercury, which makes up about 50 percent of the compound, is used to bind the metals together and to provide a strong, hard, durable filling. After years of research, mercury has been found to be the only eleme...
- What is Orofacial Pain?
Orofacial pain includes a number of clinical problems involving the chewing (masticatory) muscles or temporomandibular joint. Problems can include temporomandibular joint discomfort; muscle spasms in the head, neck and jaw; migraines, cluster or frequent headaches; or pain with the teeth, face or jaw. You swallow approximately 2,000 times per day, which causes the upper and lower teeth t...
- What is a Composite Resin (White Filling)?
What is a Composite Resin (White Filling)? A composite filling is a tooth-colored plastic and glass mixture used to restore decayed teeth. Composites are also used for cosmetic improvements of the smile by changing the color of the teeth or reshaping disfigured teeth. How is a composite placed? Following preparation, the dentist ...
- Are You Biting Off More Than You Can Chew?
In our fast-paced lives, many of us may be eating in a hurry, taking giant bites of our food to get done quickly and on to the next task. Fast-food restaurants advertise giant burgers and sandwiches as a selling point, but often those super-sized delicacies are larger than a human mouth. Taking bites that are too big to chew could be bad for your jaw and teeth, says the Academy of Genera...
- The History of Dental Advances
The History of Dental Advances Many of the most common dental tools were used as early as the Stone Age. Thankfully, technology and continuing education have made going to the dentist a much more pleasant – and painless – experience. Here is a look at the history of dentistry's most common tools, and how they came to be vital components of our oral health care needs. Where did t...
- Check Menstrual Calendar for Tooth Extraction
Dry socket, the most common postoperative complication from tooth extractions, delays the normal healing process and results when the newly formed blood clot in the extraction site does not form correctly or is prematurely lost. This blood clot lays the foundation for new tissue and bone to develop over a two-month healing process. Updated: October 2008
- Headaches and Jaw Pain? Check Your Posture!
If you experience frequent headaches and pain in your lower jaw, check your posture and consult your dentist about temporomandibular disorder (TMD), recommends the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing dental education. Poor posture places the spine in a position that causes stress to the jaw joint. When people slouch or hunch over...
- Men: Looking for a Better Job? Start by Visiting the Dentist
Men: Looking for a Better Job? Start by Visiting the Dentist An online poll of 289 general dentists and consumers confirms the traditional stereotype that men are less likely to visit the dentist than their female counterparts, according to the Academy of General Dentistry (AGD), an organization of general dentists dedicated to continuing dental education. Why? Nearly 45 percent...
- Why is Oral Health Important for Men?
Why is Oral Health Important for Men? Men are less likely than women to take care of their physical health and, according to surveys and studies, their oral health is equally ignored. Good oral health recently has been linked with longevity. Yet, one of the most common factors associated with infrequent dental checkups is just being male. Men are less likely than women to seek preventive ...
- What is Baby Bottle Tooth Decay?
What is Baby Bottle Tooth Decay? Baby bottle tooth decay is caused by the frequent and long-term exposure of a child's teeth to liquids containing sugars. Among these liquids are milk, formula, fruit juice, sodas and other sweetened drinks. The sugars in these liquids pool around the infant's teeth and gums, feeding the bacteria in plaque. Every time a child consumes a sugary liquid, acid...
- Pacifiers Have Negative and Positive Effects
Pacifiers Have Negative and Positive Effects It’s one of the hardest habits to break and can require a great deal of persuasion: Parents often struggle with weaning their child off of a pacifier. There is much debate regarding the use of pacifiers, but there is evidence to show that there are both pros and cons, according to a study in the January/February 2007 issue of Gene...
- Is My Child at Risk for Early Childhood Tooth Decay?
Is My Child at Risk for Early Childhood Tooth Decay? The average healthy adult visits the dentist twice a year. The average healthy 2-year-old has never been to the dentist. By kindergarten, 25 percent of children have never seen a dentist, yet dental decay is the single most common chronic childhood disease in America. The culprit? A combination of misinformation about when a c...
- When Should My Child First See a Dentist?
When Should My Child First See a Dentist? Your child's first visit to the dentist should happen before his or her first birthday. The general rule is six months after eruption of the first tooth. Taking your child to the dentist at a young age is the best way to prevent problems such as tooth decay, and can help parents learn how to clean their child's teeth and identify his or her fluori...
- How Do I Care for My Child's Baby Teeth?
How Do I Care for My Child’s Baby Teeth? Though you lose them early in life, your primary teeth, also called baby teeth, are essential in the development and placement of your permanent teeth. Primary teeth maintain the spaces where permanent teeth will erupt and help develop proper speech patterns that would otherwise be difficult; without maintenance of these spaces, crowding and misali...